Stella Bain is an American woman who served as a British nurse's aid in World War I. She is suffering from amnesia. She goes to London because she knows she needs to get to the Admiralty. After being found at a park in London and rather ill, she is taken in by Dr. Bridge and his wife, Lily. While she recovers from her illness, Dr. Bridge tries to help her overcome her amnesia through talk therapy.
After several visits to the Admiralty, Stella finally has a breakthrough. Someone recognizes her and says her real name, Etna Bliss. The first thing Etna remembers is that she has children.
The story unfolds from there as Etna returns to America to face her abusive husband and try to regain custody of her children. It also flashes back to the time Etna spent serving in the war. A custody hearing and more therapy after being diagnosed with "shell shock" ensue before Etna finally has her children back.